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“BPC-157 has not been proven safe or effective for any condition and is not eligible for inclusion on the 503B Bulks List for compounding.” — FDA Review Memorandum, 2023 In other words, BPC‑157 does not meet FDA standards for legal use in clinical practice

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Moreover, as previously discussed, in a cecal ligation and puncture (CLP)-induced polymicrobial sepsis model, the conditional depletion of GPX4 triggers excessive lipid peroxidation and aggravates systemic inflammatory response that reportedly rely on GSDMD-dependent pyroptosis rather than ferroptosis [12]